1,056 research outputs found
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Morphologies of laser-induced damage in hafnia-silica multilayer mirror and polarizer coatings
Hafnium-silica multilayer mirrors and polarizers were deposited by e-beam evaporation onto BK7 glass substrates. The mirrors and polarizers were coated for operation at 1053 nm at 45{degree} and at Brewster`s angle (56{degree}), respectively. They were tested with a single 3-ns laser pulse. Morphology of the laser-induced damage was characterized by optical and scanning electron microscopy. Four distinct damage morphologies were found: pits, flatbottom pits, scalds, and delaminates. The pits and flat bottom pits (<30{mu}m dia) were detected at lower fluences (as low as 5 J/cm{sup 2}). The pits seemed to result from ejection of nodular defects by causing local enhancement of the electric field. Scalds and delaminates could be observed at higher fluences (above 13 J/cm{sup 2}) and seemed to result from the formation of plasmas on the surface. These damage types often originated at pits and were less than 300 {mu}m diameter; their size increased almost linearly with fluence. Finally, effects of the damage on the beam (reflectivity degradation and phase modulations) were measured
Stochastic Interdigitation As a Toughening Mechanism at the Interface between Tendon and Bone
AbstractReattachment and healing of tendon to bone poses a persistent clinical challenge and often results in poor outcomes, in part because the mechanisms that imbue the uninjured tendon-to-bone attachment with toughness are not known. One feature of typical tendon-to-bone surgical repairs is direct attachment of tendon to smooth bone. The native tendon-to-bone attachment, however, presents a rough mineralized interface that might serve an important role in stress transfer between tendon and bone. In this study, we examined the effects of interfacial roughness and interdigital stochasticity on the strength and toughness of a bimaterial interface. Closed form linear approximations of the amplification of stresses at the rough interface were derived and applied in a two-dimensional unit-cell model. Results demonstrated that roughness may serve to increase the toughness of the tendon-to-bone insertion site at the expense of its strength. Results further suggested that the natural tendon-to-bone attachment presents roughness for which the gain in toughness outweighs the loss in strength. More generally, our results suggest a pathway for stochasticity to improve surgical reattachment strategies and structural engineering attachments
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Comparison of Structure and Properties of Femtosecond and Nanosecond Laser-Structured Silicon
We compare the optical properties, chemical composition, and crystallinity of silicon microstructures formed in the presence of SF6 by femtosecond laser irradiation and by nanosecond laser irradiation. In spite of very different morphology and crystallinity, the optical properties and chemical composition of the two types of microstructures are very similar. The structures formed with femtosecond (fs) pulses are covered with a disordered nanocrystalline surface layer less than 1 um thick, while those formed with nanosecond (ns) pulses have very little disorder. Both ns-laser-formed and fs-laser-formed structures absorb near-infrared (1.1 – 2.5 um) radiation strongly and have roughly 0.5% sulfur impurities.Engineering and Applied Science
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Growth of laser-induced damage during repetitive illumination of HfO2-SiO2 multilayer mirror and polarizer coatings
As peak fluence of high power lasers is increased, it becomes necessary to tolerate damage on mirrors, polarizers. To study how different types of damage morphologies initiate and grow during repetitive illumination, hafnia-silica multilayer mirror and polarizer coatings were laser damage tested. The coatings were prepared by e-beam evaporation and irradiated with a 3-ns pulse at 1064 nm. The damage morphology was recorded after each shot to determine the types of damage that cause massive unstable failure and lower the optic`s functional damage threshold. Results were summarized on damage stability maps plotting the average damage size vs number of shots for fluences ranging from 10 to 40 J/cm{sup 2}. The maps indicate that the commonly observed damage morphologies (pits, flat bottom pits, scalds, outer layer delamination) have distinct growth behaviors and influence the value of the functional damage threshold differently. While pits are stable up to fluences as high as 40 J/cm{sup 2}, flat bottom pits can grow during repetitive illumination above a critical fluence of about 35 J/cm{sup 2}. Scalds are formed in the first shot and never grow at fluences below 40 J/cm{sup 2}. Finally, delaminates are highly unstable and have the potential for damaging the coating catastrophically above 15 J/cm{sup 2}. Results show that delaminate damage should be prevented; this knowledge has allowed coatings development efforts to focus on eliminating the origin of such damage morphology
Contact complete integrability
Complete integrability in a symplectic setting means the existence of a
Lagrangian foliation leaf-wise preserved by the dynamics. In the paper we
describe complete integrability in a contact set-up as a more subtle structure:
a flag of two foliations, Legendrian and co-Legendrian, and a
holonomy-invariant transverse measure of the former in the latter. This turns
out to be equivalent to the existence of a canonical
structure on the leaves of the co-Legendrian foliation. Further, the above
structure implies the existence of contact fields preserving a special
contact 1-form, thus providing the geometric framework and establishing
equivalence with previously known definitions of contact integrability. We also
show that contact completely integrable systems are solvable in quadratures. We
present an example of contact complete integrability: the billiard system
inside an ellipsoid in pseudo-Euclidean space, restricted to the space of
oriented null geodesics. We describe a surprising acceleration mechanism for
closed light-like billiard trajectories
An ex vivo culture model of kidney podocyte injury reveals mechanosensitive, synaptopodin-templating, sarcomere-like structures
Chronic kidney diseases are widespread and incurable. The biophysical mechanisms underlying them are unclear, in part because material systems for reconstituting the microenvironment of relevant kidney cells are limited. A critical question is how kidney podocytes (glomerular epithelial cells) regenerate foot processes of the filtration apparatus following injury. Recently identified sarcomere-like structures (SLSs) with periodically spaced myosin IIA and synaptopodin appear in injured podocytes in vivo. We hypothesized that SLSs template synaptopodin in the initial stages of recovery in response to microenvironmental stimuli and tested this hypothesis by developing an ex vivo culture system that allows control of the podocyte microenvironment. Results supported our hypothesis. SLSs in podocytes that migrated from isolated kidney glomeruli presented periodic synaptopodin-positive clusters that nucleated peripheral, foot process-like extensions. SLSs were mechanoresponsive to actomyosin inhibitors and substrate stiffness. Results suggest SLSs as mechanobiological mediators of podocyte recovery and as potential targets for therapeutic intervention
Micro-mechanical properties of the tendon-to-bone attachment
The tendon-to-bone attachment (enthesis) is a complex hierarchical tissue that connects stiff bone to compliant tendon. The attachment site at the micrometer scale exhibits gradients in mineral content and collagen orientation, which likely act to minimize stress concentrations. The physiological micromechanics of the attachment thus define resultant performance, but difficulties in sample preparation and mechanical testing at this scale have restricted understanding of structure-mechanical function. Here, microscale beams from entheses of wild type mice and mice with mineral defects were prepared using cryo-focused ion beam milling and pulled to failure using a modified atomic force microscopy system. Micromechanical behavior of tendon-to-bone structures, including elastic modulus, strength, resilience, and toughness, were obtained. Results demonstrated considerably higher mechanical performance at the micrometer length scale compared to the millimeter tissue length scale, describing enthesis material properties without the influence of higher order structural effects such as defects. Micromechanical investigation revealed a decrease in strength in entheses with mineral defects. To further examine structure-mechanical function relationships, local deformation behavior along the tendon-to-bone attachment was determined using local image correlation. A high compliance zone near the mineralized gradient of the attachment was clearly identified and highlighted the lack of correlation between mineral distribution and strain on the low-mineral end of the attachment. This compliant region is proposed to act as an energy absorbing component, limiting catastrophic failure within the tendon-to-bone attachment through higher local deformation. This understanding of tendon-to-bone micromechanics demonstrates the critical role of micrometer scale features in the mechanics of the tissue
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Thin film contamination effects on laser-induced damage of fused silica surfaces at 355 nm
Fused silica windows were artificially contaminated to estimate the resistance of target chamber debris shields against laser damage during NIF operation. Uniform contamination thin films (1 to 5 nm thick) were prepared by sputtering various materials (Au, Al, Cu, and B4C). The loss of transmission of the samples was first measured. They were then tested at 355 nm in air with an 8-ns Nd:YAG laser. The damage morphologies were characterized by Nomarski optical microscopy and SEM. Both theory and experiments showed that metal contamination for films as thin as 1 nm leads to a substantial loss of transmission. The laser damage resistance dropped very uniformly across the entire surface (e.g. 6 J/cm2 for 5 nm of Cu). The damage morphology characterization showed that contrary to clean silica, metal coated samples did not produce pits on the surface. B4C coated silica, on the other hand, led to a higher density of such damage pits. A model for light absorption in the thin film was coupled with a simple heat deposition and diffusion model to perform preliminary theoretical estimates of damage thresholds. The estimates of the loss due to light absorption and reflection pointed out significant .differences between metals (e.g. Al and Au). The damage threshold predictions were in qualitative agreement with experimental measurements
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Cellular mechanosensing of the biophysical microenvironment: A review of mathematical models of biophysical regulation of cell responses.
Cells in vivo reside within complex microenvironments composed of both biochemical and biophysical cues. The dynamic feedback between cells and their microenvironments hinges upon biophysical cues that regulate critical cellular behaviors. Understanding this regulation from sensing to reaction to feedback is therefore critical, and a large effort is afoot to identify and mathematically model the fundamental mechanobiological mechanisms underlying this regulation. This review provides a critical perspective on recent progress in mathematical models for the responses of cells to the biophysical cues in their microenvironments, including dynamic strain, osmotic shock, fluid shear stress, mechanical force, matrix rigidity, porosity, and matrix shape. The review highlights key successes and failings of existing models, and discusses future opportunities and challenges in the field.This work was supported by the National Natural Science Foundation of China (11372243, 11522219, 11532009, 11402192), the Chinese Ministry of Education through a Changjiang Scholar award to GMG, the National Institutes of Health through grants U01EB016422 and R01HL109505, and the NSF Science and Technology Center for Engineering Mechanobiology, grant CMMI 1548571
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